COLING 2025main23 citations

AI Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulator

Zhihao Fan, Lai Wei, Jialong Tang, Wei Chen, Wang Siyuan, Zhongyu Wei, Fei Huang

Abstract

Artificial intelligence has significantly revolutionized healthcare, particularly through large language models (LLMs) that demonstrate superior performance in static medical question answering benchmarks. However, evaluating the potential of LLMs for real-world clinical applications remains challenging due to the intricate nature of doctor-patient interactions. To address this, we introduce AI Hospital, a multi-agent framework emulating dynamic medical interactions between Doctor as player and NPCs including Patient and Examiner. This setup allows for more practical assessments of LLMs in simulated clinical scenarios. We develop the Multi-View Medical Evaluation (MVME) benchmark, utilizing high-quality Chinese medical records and multiple evaluation strategies to quantify the performance of LLM-driven Doctor agents on symptom collection, examination recommendations, and diagnoses. Additionally, a dispute resolution collaborative mechanism is proposed to enhance medical interaction capabilities through iterative discussions. Despite improvements, current LLMs (including GPT-4) still exhibit significant performance gaps in multi-turn interactive scenarios compared to non-interactive scenarios. Our findings highlight the need for further research to bridge these gaps and improve LLMs’ clinical decision-making capabilities. Our data, code, and experimental results are all open-sourced at https://github.com/LibertFan/AI_Hospital.

BibTeX
@inproceedings{fan-etal-2025-ai,
    title = "{AI} Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulator",
    author = "Fan, Zhihao  and
      Wei, Lai  and
      Tang, Jialong  and
      Chen, Wei  and
      Siyuan, Wang  and
      Wei, Zhongyu  and
      Huang, Fei",
    editor = "Rambow, Owen  and
      Wanner, Leo  and
      Apidianaki, Marianna  and
      Al-Khalifa, Hend  and
      Eugenio, Barbara Di  and
      Schockaert, Steven",
    booktitle = "Proceedings of the 31st International Conference on Computational Linguistics",
    month = jan,
    year = "2025",
    address = "Abu Dhabi, UAE",
    publisher = "Association for Computational Linguistics",
    url = "https://aclanthology.org/2025.coling-main.680/",
    pages = "10183--10213"
}
AI Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulator · COLING 2025