Low-resolution reconstruction of intensity functions on the sphere for single-particle diffraction imaging
Julien Flamand, Nicolas Le Bihan, Andrew V. Martin, Jonathan H. Manton
Abstract
Single-particle imaging experiments using X-ray Free-Electron Lasers (XFEL) belong to a new generation of X-ray imaging techniques potentially allowing high resolution images of non-crystallizable molecules to be obtained. One of the challenges of single-particle imaging is the reconstruction of the 3D intensity function from only a few samples collected on a planar detector after the interaction of a free falling molecule and the X-ray beam. In this paper, we take advantage of the symmetries of the intensity function to propose an original low-resolution reconstruction algorithm based on an Expansion Maximization Compression (EMC) approach. We study the problem of adequate sampling of the rotation group via simulation to illustrate the potential of the approach.
BibTeX
@inproceedings{icassp2016_lowresolutionrec,
title = {Low-resolution reconstruction of intensity functions on the sphere for single-particle diffraction imaging},
author = {Julien Flamand and Nicolas Le Bihan and Andrew V. Martin and Jonathan H. Manton},
booktitle = {ICASSP 2016},
year = {2016}
}