ADHD Disease Detection Based on Short- and Long-Term Brain Function Encoding and Memory Graph Network

Abstract

Graph-based attention deficit hyperactivity disorder (ADHD) detection methods have been extensively studied, but comparatively less attention has been paid to short-term brain functional reorganization. In this paper, we propose an ADHD disease detection model based on short- and long-term brain function encoding and memory graph network. We first exploit a novel brain map sequence construction method based on short-term windows to extract short-term brain function features. Then, we design a short-term state and temporal dependency encoder to characterize short-term sequence patterns of brain function. Furthermore, a brain function memory is introduced to capture the association of brain activity patterns and historical sequence patterns. Concurrently, GNN-based long-term brain function feature extraction network is used to extract brain structure features, which are fused with short-term features for ADHD detection. Experimental validation on the publicly available neuroimaging datasets ADHD-200 and OpenNeuro-ds002424 demonstrates the superior performance of our model in brain disorder detection.