CHAMMI: A benchmark for channel-adaptive models in microscopy imaging
Zitong Chen, Chau Pham, Siqi Wang, Michael Doron, Nikita Moshkov, Bryan A. Plummer, Juan C Caicedo
Abstract
Most neural networks assume that input images have a fixed number of channels (three for RGB images). However, there are many settings where the number of channels may vary, such as microscopy images where the number of channels changes depending on instruments and experimental goals. Yet, there has not been a systemic attempt to create and evaluate neural networks that are invariant to the number and type of channels. As a result, trained models remain specific to individual studies and are hardly reusable for other microscopy settings. In this paper, we present a benchmark for investigating channel-adaptive models in microscopy imaging, which consists of 1) a dataset of varied-channel single-cell images, and 2) a biologically relevant evaluation framework. In addition, we adapted several existing techniques to create channel-adaptive models and compared their performance on this benchmark to fixed-channel, baseline models. We find that channel-adaptive models can generalize better to out-of-domain tasks and can be computationally efficient. We contribute a curated dataset and an evaluation API to facilitate objective comparisons in future research and applications.
BibTeX
@inproceedings{
chen2023chammi,
title={{CHAMMI}: A benchmark for channel-adaptive models in microscopy imaging},
author={Zitong Chen and Chau Pham and Siqi Wang and Michael Doron and Nikita Moshkov and Bryan A. Plummer and Juan C Caicedo},
booktitle={Thirty-seventh Conference on Neural Information Processing Systems Datasets and Benchmarks Track},
year={2023},
url={https://openreview.net/forum?id=Luc1bZLeMY}
}