2026
GenUnfold: Rapidly Predict Protein Mechanical Unfolding Trajectory via a Physics-Guided Diffusion Model
ICML 2026poster
Many fundamental biological processes are governed by mechanical forces, with proteins acting as the key molecular mediators. Elucidating how protein unfolding responds to force is critical for understanding the mechano-pathologies, such as cardiomyopathy and muscular dystrophy. While the unfolding …