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Cheng Guo

5 accepted papers

2026

MultiGeo: Predicting Drug-Target Affinity via Adaptive Multi-Conformation Ensemble Learning

IJCAI 2026

Predicting drug–target affinity (DTA) is central to drug discovery, yet most deep learning models rely on a single static protein structure, neglecting the conformational heterogeneity that underlies many binding mechanisms. We propose MultiGeo, a DTA prediction framework that explicitly leverages m

Cited by 0Scholar
2025

Physics-Informed Learning for Human Whole-Body Kinematics Prediction via Sparse IMUs

IROS 2025

Accurate and physically feasible human motion prediction is crucial for safe and seamless human-robot collaboration. While recent advancements in human motion capture enable real-time pose estimation, the practical value of many existing approaches is limited by the lack of future predictions and co

Cited by 0SourceScholar
2025

SDBench: A Survey-based Domain-specific LLM Benchmarking and Optimization Framework

ACL 2025long

The rapid advancement of large language models (LLMs) in recent years has made it feasible to establish domain-specific LLMs for specialized fields. However, in practical development, acquiring domain-specific knowledge often requires a significant amount of professional expert manpower. Moreover, e…

Cited by 0SourcePDFScholar
2023

Learning a Practical SDR-to-HDRTV Up-Conversion Using New Dataset and Degradation Models

CVPR 2023poster

In media industry, the demand of SDR-to-HDRTV up-conversion arises when users possess HDR-WCG (high dynamic range-wide color gamut) TVs while most off-the-shelf footage is still in SDR (standard dynamic range). The research community has started tackling this low-level vision task by learning-based…

2021

Physics-Based Iterative Projection Complex Neural Network for Phase Retrieval in Lensless Microscopy Imaging

CVPR 2021poster

Phase retrieval from intensity-only measurements plays a central role in many real-world imaging tasks. In recent years, deep neural networks based methods emerge and show promising performance for phase retrieval. However, their interpretability and generalization still remain a major challenge. In…

Cited by 37PDFScholar