6 accepted papers
Multi-objective molecular optimization is a fundamental yet inherently challenging task in drug discovery, as it requires simultaneously optimizing multiple, often conflicting, molecular properties. Although recent deep learning methods have shown promise, they often lack objective-specific special
Chemical reaction and retrosynthesis prediction are fundamental tasks in drug discovery. Recently, large language models (LLMs) have shown potential in many domains. However, directly applying LLMs to these tasks faces two major challenges: (i) lacking a large-scale chemical synthesis-related instru
Large language models exhibit high-level commonsense reasoning abilities, especially with enhancement methods like Chain-of-Thought (CoT). However, we find these CoT-like methods lead to a considerable number of originally correct answers turning wrong, which we define as the Toxic CoT problem. To i…
In this paper, we focus on the challenging yet practical problem of Continual Few-shot Relation Extraction (CFRE), which involves extracting relations in the continuous and iterative arrival of new data with only a few labeled examples. The main challenges in CFRE are overfitting due to few-shot lea…
Adjusting the outdated behaviors of large langugae models (LLMs) after deployment remains a significant challenge. It motivates the model editing research, which is however mainly explored in a restricted task form with triple-based edit requests. Recent works have initiated a transition to a more p…
Large Language Models (LLMs) have shown impressive capabilities but still suffer from the issue of hallucinations. A significant type of this issue is the false premise hallucination, which we define as the phenomenon when LLMs generate hallucinated text when confronted with false premise questions.…