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David A. Knowles

3 accepted papers

2026

Interpretable Neural ODEs for Gene Regulatory Network Discovery under Perturbations

ICML 2026poster

Modern high-throughput biological datasets containing thousands of perturbations enable large-scale discovery of causal graphs that represent regulatory interactions between genes. Differentiable causal graphical models and regression-based methods have been developed to infer gene regulatory networ…

Cited by 0SourceScholar
2024

Disentangling Interpretable Factors with Supervised Independent Subspace Principal Component Analysis

NeurIPS 2024poster

The success of machine learning models relies heavily on effectively representing high-dimensional data. However, ensuring data representations capture human-understandable concepts remains difficult, often requiring the incorporation of prior knowledge and decomposition of data into multiple subspa…