Dazhi Lu — accepted AI-conference papers

2025

SWAMamba: A Sliding Window Attention Mamba Framework for Predicting Translation Elongation Rates

Xi Zeng, Fei Ni, Shaoqing Jiao, Dazhi Lu, Jianye Hao, Jiajie Peng

AAAI 2025technical

Translation elongation is essential for cellular proteostasis and is implicated in cancer and neurodegeneration. Accurately predicting the rate of ribosome elongation in each codon (also called ribosomal A site) on mRNA is important for understanding and modulating protein synthesis. However, predic…

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2024

Designing Biological Sequences without Prior Knowledge Using Evolutionary Reinforcement Learning

Xi Zeng, Xiaotian Hao, Hongyao Tang, Zhentao Tang, Shaoqing Jiao, Dazhi Lu +1

AAAI 2024technical

Designing novel biological sequences with desired properties is a significant challenge in biological science because of the extra large search space. The traditional design process usually involves multiple rounds of costly wet lab evaluations. To reduce the need for expensive wet lab experiments,…

Cited by 2 Source ↗PDF ↗code ↗Scholar ↗