Hanyuan Xie

CPSea: Large-scale cyclic peptide-protein complex dataset for machine learning in cyclic peptide design

Cyclic peptides exhibit better binding affinity and proteolytic stability compared to their linear counterparts. However, the development of cyclic peptide design models is hindered by the scarcity of data. To address this, we introduce **CPSea**(**C**yclic **P**eptide **Sea**), a dataset of 2.71 mi…