NeuronCtrl: Geometry-Aware Safe Closed-Loop Generative Control for Neuronal Microenvironment Dynamics
Neuromodulation can be viewed as closed-loop control of high-dimensional spatiotemporal fields on irregular 3D morphologies, coupling membrane electrophysiology with ionic reaction–diffusion. This view supports high-rate feedback and systematic in-silico evaluation, yet is difficult in practice. Unl…