4 accepted papers
Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually learn. In this work, we conduct a systematic study of repre…
Understanding cellular responses to stimuli is crucial for biological discovery and drug development. Transcriptomics provides interpretable, gene-level insights, while microscopy imaging offers rich predictive features but is harder to interpret. Weakly paired datasets, where samples share biologic…
Deriving insights from experimentally generated datasets requires methods that can account for random and systematic measurement errors and remove them in order to accurately represent the underlying effects of the conditions being tested. Here we present a framework for pretraining on large-scale m…
Unlike color photography images which are consistently encoded into RGB channels biological images encompass various modalities where the type of microscopy and the meaning of each channel varies with each experiment. Importantly the number of channels can range from one to a dozen and their correla…