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Johannes C. Paetzold

7 accepted papers

2026

BackSplit: The Importance of Sub-dividing the Background in Biomedical Lesion Segmentation

CVPR 2026

Segmenting small lesions in medical images remains notoriously difficult. Most prior work tackles this challenge by either designing better architectures, loss functions, or data augmentation schemes; and collecting more labeled data. We take a different view, arguing that part of the problem lies i

Cited by 0SourceScholar
2025

Topograph: An Efficient Graph-Based Framework for Strictly Topology Preserving Image Segmentation

ICLR 2025spotlight

Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust topological guarantees, are limited to specific use cases, o…

Cited by 4SourcePDFScholar
2024

Physics-Regularized Multi-Modal Image Assimilation for Brain Tumor Localization

NeurIPS 2024poster

Physical models in the form of partial differential equations serve as important priors for many under-constrained problems. One such application is tumor treatment planning, which relies on accurately estimating the spatial distribution of tumor cells within a patient’s anatomy. While medical imagi…

2023

A Skeletonization Algorithm for Gradient-Based Optimization

ICCV 2023poster

The skeleton of a digital image is a compact representation of its topology, geometry, and scale. It has utility in many computer vision applications, such as image description, segmentation, and registration. However, skeletonization has only seen limited use in contemporary deep learning solutions…

Cited by 15PDFcodeScholar
2023

Topologically Faithful Image Segmentation via Induced Matching of Persistence Barcodes

ICML 2023poster

Segmentation models predominantly optimize pixel-overlap-based loss, an objective that is actually inadequate for many segmentation tasks. In recent years, their limitations fueled a growing interest in topology-aware methods, which aim to recover the topology of the segmented structures. However, s…

2021

Whole Brain Vessel Graphs: A Dataset and Benchmark for Graph Learning and Neuroscience

NeurIPS 2021poster

Biological neural networks define the brain function and intelligence of humans and other mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is closely interconnected with the spatial organization of the brain's microvasculature, which supplies oxygen to the neuro…

Cited by 28SourceScholar
2021

clDice - A Novel Topology-Preserving Loss Function for Tubular Structure Segmentation

CVPR 2021poster

Accurate segmentation of tubular, network-like structures, such as vessels, neurons, or roads, is relevant to many fields of research. For such structures, the topology is their most important characteristic; particularly preserving connectedness: in the case of vascular networks, missing a connecte…

Cited by 327PDFcodeScholar