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Joseph H. Davis

2 accepted papers

2021

CryoDRGN2: Ab Initio Neural Reconstruction of 3D Protein Structures From Real Cryo-EM Images

ICCV 2021poster

Protein structure determination from cryo-EM data requires reconstructing a 3D volume (or distribution of volumes) from many noisy and randomly oriented 2D projection images. While the standard homogeneous reconstruction task aims to recover a single static structure, recently-proposed neural and no…

Cited by 85PDFScholar
2020

Reconstructing continuous distributions of 3D protein structure from cryo-EM images

ICLR 2020spotlight

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structure of proteins and other macromolecular complexes at near-atomic resolution. In single particle cryo-EM, the central problem is to reconstruct the 3D structure of a macromolecule from $10^{4-7}$ noisy and randomly…

Cited by 127SourceScholar