2026
BioToken and BioFM – Biologically-Informed Tokenization Enables Accurate and Efficient Genomic Foundation Models
Aleksandr Medvedev, Karthik Viswanathan, Praveenkumar Kanithi, Kirill Vishniakov, Prateek Munjal, Clement Christophe +4
ICML 2026poster
Existing genomic foundation models (GFMs) typically treat DNA as raw nucleotide sequences, often overlooking the regulatory context required to interpret genetic variation accurately. We introduce BioToken, a tokenization framework that directly encodes variants and biological annotations into genom…