2026
PepCompass: Navigating Peptide Embedding Spaces Using Riemannian Geometry
Marcin Możejko, Adam Bielecki, Jurand Prądzyński, Marcin Traskowski, Antoni Janowski, Hyun-Su Lee +7
ICML 2026poster
Antimicrobial peptide discovery is challenged by the astronomical size of peptide space and the relative scarcity of active peptides. While generative models provide latent maps of this space, they typically ignore decoder-induced geometry and rely on flat Euclidean metrics, making exploration disto…