← Search

Mikel Landajuela

5 accepted papers

2026

Machine Learning Models Assisting the Development of Antibody Therapeutics and Vaccines – an Emerging Trend

AAAI 2026technical

The development of novel effective medical treatments is one of the most important and expected beneficial effects of the AI revolution. This decade is witnessing the rise of AI models able to predict complex properties for protein-protein interactions that hold great promise in assisting in the dev

Cited by 0SourcePDFScholar
2025

DisCo-DSO: Coupling Discrete and Continuous Optimization for Efficient Generative Design in Hybrid Spaces

AAAI 2025technical

We consider the challenge of black-box optimization within hybrid discrete-continuous and variable-length spaces, a problem that arises in various applications, such as decision tree learning and symbolic regression. We propose DisCo-DSO (Discrete-Continuous Deep Symbolic Optimization), a novel appr…

2022

A Unified Framework for Deep Symbolic Regression

NeurIPS 2022accept

The last few years have witnessed a surge in methods for symbolic regression, from advances in traditional evolutionary approaches to novel deep learning-based systems. Individual works typically focus on advancing the state-of-the-art for one particular class of solution strategies, and there have…

Cited by 96SourcePDFScholar
2021

Discovering symbolic policies with deep reinforcement learning

ICML 2021spotlight

Deep reinforcement learning (DRL) has proven successful for many difficult control problems by learning policies represented by neural networks. However, the complexity of neural network-based policies{—}involving thousands of composed non-linear operators{—}can render them problematic to understand…

Cited by 135SourcePDFScholar
2021

Symbolic Regression via Deep Reinforcement Learning Enhanced Genetic Programming Seeding

NeurIPS 2021poster

Symbolic regression is the process of identifying mathematical expressions that fit observed output from a black-box process. It is a discrete optimization problem generally believed to be NP-hard. Prior approaches to solving the problem include neural-guided search (e.g. using reinforcement learnin…