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Mingming Zhu

2 accepted papers

2026

Advancing Protein Design via Multi-Agent Reinforcement Learning with Pareto-Based Collaborative Optimization

AAAI 2026technical

Protein design is revolutionizing biotechnology, yet existing approaches struggle to balance structural foldability with functional performance. Structure-based models excel at generating stable protein backbones but often overlook critical functional properties, while protein language models captur

Cited by 1SourcePDFScholar
2025

Accurately Predicting Protein Mutational Effects via a Hierarchical Many-Body Attention Network

NeurIPS 2025poster

Predicting changes in binding free energy ($\Delta\Delta G$) is essential for understanding protein-protein interactions, which are critical in drug design and protein engineering. However, existing methods often rely on pre-trained knowledge and heuristic features, limiting their ability to accurat…

Cited by 0SourceScholar