CryoSWD: Sliced Wasserstein Distance Minimization for 3D Reconstruction in Cryo-electron Microscopy
Single particle reconstruction (SPR) in cryo-electron microscopy (cryo-EM) is a prominent imaging method that recovers the 3D shape of a biomolecule, given a large number of its noisy projections from random and unknown views. Recently, CryoGAN [1] cast SPR as an unsupervised distribution matching p…