3 accepted papers
The intersection of AI and biology has entered a phase of explosive growth, driven by the ambition to build "Virtual Cells" or computational models capable of predicting cellular responses to any perturbation. Following the success of structural biology (e.g., AlphaFold) and large language models, t…
Computational modeling of single-cell gene expression is crucial for understanding cellular processes, but generating realistic expression profiles remains a major challenge. This difficulty arises from the count nature of gene expression data and complex latent dependencies among genes. Existing ge…
Predicting disease risk from DNA presents an unprecedented emerging challenge as biobanks approach population scale sizes ($N>10^6$ individuals) with ultra-high-dimensional features ($L>10^5$ genotypes). Current methods, often linear and reliant on summary statistics, fail to capture complex genetic…