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Petr Kouba

2 accepted papers

2025

Learning to engineer protein flexibility

ICLR 2025poster

Generative machine learning models are increasingly being used to design novel proteins. However, their major limitation is the inability to account for protein flexibility, a property crucial for protein function. Learning to engineer flexibility is difficult because the relevant data is scarce, he…

2024

Learning to design protein-protein interactions with enhanced generalization

ICLR 2024poster

Discovering mutations enhancing protein-protein interactions (PPIs) is critical for advancing biomedical research and developing improved therapeutics. While machine learning approaches have substantially advanced the field, they often struggle to generalize beyond training data in practical scenari…

Cited by 19SourcePDFScholar