Ranhao Zhang

Fast Alignment Algorithm for Cryo-EM Particle Images Based on Harmonic Analysis

Cryo-electron microscopy (Cryo-EM) is a revolutionizing technique that facilitates the determination of macromolecule structures. To attain high-resolution structures, numerous noisy images should be iteratively aligned and reconstructed into 3D models. The alignment step is the bottleneck of comput…