12 accepted papers
Spatial transcriptomics (ST) is a novel technology that enables the observation of gene expression at the resolution of individual spots within pathological tissues. ST quantifies the expression of tens of thousands of genes in a tissue section; however, heavy observational noise is often introduced
Estimating slide- and patch-level gene expression profiles from pathology images enables rapid and low-cost molecular analysis with broad clinical impact. Despite strong results, existing approaches treat gene expression as a mere slide- or spot-level signal and do not incorporate the fact that the
Active learning (AL) is a label-efficient machine learning paradigm that focuses on selectively annotating high-value instances to maximize learning efficiency. Its effectiveness can be further enhanced by incorporating weak supervision, which uses rough yet cost-effective annotations instead of exa…
Gene expression estimation from pathology images has the potential to reduce the RNA sequencing cost. Point-wise loss functions have been widely used to minimize the discrepancy between predicted and absolute gene expression values. However, due to the complexity of the sequencing techniques and in…
The paper proposes a novel problem in multi-class Multiple-Instance Learning (MIL) called Learning from the Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag’s label. LML aims to classify instances using bag-level majority classes. This problem is valuable…
This paper proposes a novel and efficient method for Learning from Label Proportions (LLP), whose goal is to train a classifier only by using the class label proportions of instance sets, called bags. We propose a novel LLP method based on an online pseudo-labeling method with regret minimization. A…
Learning from label proportions (LLP) is a promising weakly supervised learning problem. In LLP, a set of instances (bag) has label proportions but no instance-level labels. LLP aims to train an instance-level classifier by using the label proportions of the bag. In this paper, we propose a bag-le…
Conventional cell tracking methods detect multiple cells in each frame (detection) and then associate the detection results in successive time-frames (association). Most cell tracking methods perform the association task independently from the detection task. However, there is no guarantee of preser…
In pathological diagnosis, since the proportion of the adenocarcinoma subtypes is related to the recurrence rate and the survival time after surgery, the proportion of cancer subtypes for pathological images has been recorded as diagnostic information in some hospitals. In this paper, we propose a s…
We propose a weakly-supervised cell tracking method that can train a convolutional neural network (CNN) by using only the annotation of ""cell detection"" (i.e., the coordinates of cell positions) without association information, in which cell positions can be easily obtained by nuclear staining. Fi…
Automated digital histopathology image segmentation is an important task to help pathologists diagnose tumors and cancer subtypes. For pathological diagnosis of cancer subtypes, pathologists usually change the magnification of whole-slide images (WSI) viewers. A key assumption is that the importance…
Visual recognition of wet surfaces and their degrees of wetness is important for many computer vision applications. It can inform slippery spots on a road to autonomous vehicles, muddy areas of a trail to humanoid robots, and the freshness of groceries to us. In the past, monochromatic appearance ch…