Sarah A Teichmann

Estimation of single-cell and tissue perturbation effect in spatial transcriptomics via Spatial Causal Disentanglement

Models of Virtual Cells and Virtual Tissues at single-cell resolution would allow us to test perturbations in silico and accelerate progress in tissue and cell engineering. However, most such models are not rooted in causal inference and as a result, could mistake correlation for causation. We intr…