5 accepted papers
Predicting drug efficacy and safety in vivo requires information on biological responses (e.g., cell morphology and gene expression) to small molecule perturbations. However, current molecular representation learning methods do not provide a comprehensive view of cell states under these perturbation…
Drug-target interaction (DTI) prediction is crucial for identifying new therapeutics and detecting mechanisms of action. While structure-based methods accurately model physical interactions between a drug and its protein target, cell-based assays such as Cell Painting can better capture complex DTI…
Various strategies for label-scarce object detection have been explored by the computer vision research community. These strategies mainly rely on assumptions that are specific to natural images and not directly applicable to the biological and biomedical vision domains. For example, most semi-super…
In this work, we propose IndoLayout, a novel real-time approach for generating high-quality occupancy maps from an RGB image for indoor scenes. Such occupancy maps are often crucial for path-planning and mapping in indoor environments but are often built using only information contained in the ego v…
Many new applications in drug discovery and functional genomics require capturing the morphology of individual imaged cells as comprehensively as possible rather than measuring one particular feature. In these so-called profiling experiments, the goal is to compare populations of cells treated with…