Shikang Liang

Efficient Prediction of Large Protein Complexes via Subunit-Guided Hierarchical Refinement

State-of-the-art protein structure predictors have revolutionized structural biology, yet quadratic memory growth with token length makes end-to-end inference impractical for large complexes beyond a few thousand tokens. We introduce \textsc{HierAFold}, a hierarchical pipeline that exploits the modu…