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Tiantian Zhu

4 accepted papers

2026

PepCCD: A Contrastive Conditioned Diffusion Framework for Target-Specific Peptide Generation

AAAI 2026technical

Peptide-based drug design targeting “undruggable” proteins remains one of the most critical challenges in modern drug discovery. Conventional peptide-discovery pipelines rely on low-throughput experimental screening, which is both time-consuming and prohibitively expensive. Moreover, existing comput

Cited by 0SourcePDFScholar
2025

Defense Against Model Stealing Based on Account-Aware Distribution Discrepancy

AAAI 2025technical

Malicious users attempt to replicate commercial models functionally at low cost by training a clone model with query responses. It is challenging to timely prevent such model-stealing attacks to achieve strong protection and maintain utility. In this paper, we propose a novel non-parametric detector…

2023

Controllable Contrastive Generation for Multilingual Biomedical Entity Linking

EMNLP 2023long main

Multilingual biomedical entity linking (MBEL) aims to map language-specific mentions in the biomedical text to standardized concepts in a multilingual knowledge base (KB) such as Unified Medical Language System (UMLS). In this paper, we propose Con2GEN, a prompt-based controllable contrastive genera…

Cited by 0SourceScholar
2022

Enhancing Entity Representations with Prompt Learning for Biomedical Entity Linking

IJCAI 2022poster

Biomedical entity linking aims to map mentions in biomedical text to standardized concepts or entities in a curated knowledge base (KB) such as Unified Medical Language System (UMLS). The latest research tends to solve this problem in a unified framework solely based on surface form matching between…