← Search

Tiantian Zhu

4 accepted papers

2026

PepCCD: A Contrastive Conditioned Diffusion Framework for Target-Specific Peptide Generation

AAAI 2026technical

Peptide-based drug design targeting “undruggable” proteins remains one of the most critical challenges in modern drug discovery. Conventional peptide-discovery pipelines rely on low-throughput experimental screening, which is both time-consuming and prohibitively expensive. Moreover, existing comput

Cited by 0Source ↗PDF ↗Scholar ↗
2025

Defense Against Model Stealing Based on Account-Aware Distribution Discrepancy

AAAI 2025technical

Malicious users attempt to replicate commercial models functionally at low cost by training a clone model with query responses. It is challenging to timely prevent such model-stealing attacks to achieve strong protection and maintain utility. In this paper, we propose a novel non-parametric detector…

2023

Controllable Contrastive Generation for Multilingual Biomedical Entity Linking

EMNLP 2023long main

Multilingual biomedical entity linking (MBEL) aims to map language-specific mentions in the biomedical text to standardized concepts in a multilingual knowledge base (KB) such as Unified Medical Language System (UMLS). In this paper, we propose Con2GEN, a prompt-based controllable contrastive genera…

Cited by 11Source ↗Scholar ↗
2022

Enhancing Entity Representations with Prompt Learning for Biomedical Entity Linking

IJCAI 2022poster

Biomedical entity linking aims to map mentions in biomedical text to standardized concepts or entities in a curated knowledge base (KB) such as Unified Medical Language System (UMLS). The latest research tends to solve this problem in a unified framework solely based on surface form matching between…