Tiara Natasha Binte Sayuti

Generating Apoptosis-Inducing Anticancer Peptides Targeting BCL-xL Using Latent Diffusion Models on Small Datasets

The overexpression of B-cell lymphoma-extra large (BCL-xL), an anti-apoptotic protein, plays a pivotal role in various cancers by inhibiting apoptosis and promoting tumor progression. We introduce Latent Diffusion Model (LDM) specifically designed to generate apoptosis-inducing Anticancer Peptides (…