Wenpin Hou

A New Paradigm for Genome-wide DNA Methylation Prediction Without Methylation Input

DNA methylation (DNAm) is a key epigenetic modification that regulates gene expression and is pivotal in development and disease. However, profiling DNAm at genome scale is challenging: of $\textasciitilde$28 million CpG sites in the human genome, only about 1–3\% are typically assayed in common dat…