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Wesley Wei Qian

2 accepted papers

2023

3D Equivariant Diffusion for Target-Aware Molecule Generation and Affinity Prediction

ICLR 2023poster

Rich data and powerful machine learning models allow us to design drugs for a specific protein target <em>in silico</em>. Recently, the inclusion of 3D structures during targeted drug design shows superior performance to other target-free models as the atomic interaction in the 3D space is explicitl…

2022

Energy-Inspired Molecular Conformation Optimization

ICLR 2022poster

This paper studies an important problem in computational chemistry: predicting a molecule's spatial atom arrangements, or a molecular conformation. We propose a neural energy minimization formulation that casts the prediction problem into an unrolled optimization process, where a neural network is p…

Cited by 24SourcePDFScholar