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Xiaozhuan Liang

10 accepted papers

2024

BioT5+: Towards Generalized Biological Understanding with IUPAC Integration and Multi-task Tuning

ACL 2024findings

Recent research trends in computational biology have increasingly focused on integrating text and bio-entity modeling, especially in the context of molecules and proteins. However, previous efforts like BioT5 faced challenges in generalizing across diverse tasks and lacked a nuanced understanding of…

2024

InstructEdit: Instruction-Based Knowledge Editing for Large Language Models

IJCAI 2024poster

Knowledge editing for large language models can offer an efficient solution to alter a model’s behavior without negatively impacting the overall performance. However, the current approaches encounter issues with limited generalizability across tasks, necessitating one distinct editor for each task,…

2024

Mol-Instructions: A Large-Scale Biomolecular Instruction Dataset for Large Language Models

ICLR 2024poster

Large Language Models (LLMs), with their remarkable task-handling capabilities and innovative outputs, have catalyzed significant advancements across a spectrum of fields. However, their proficiency within specialized domains such as biomolecular studies remains limited. To address this challenge, w…

2024

To Forget or Not? Towards Practical Knowledge Unlearning for Large Language Models

EMNLP 2024finding

Large Language Models (LLMs) trained on extensive corpora inevitably retain sensitive data, such as personal privacy information and copyrighted material. Recent advancements in knowledge unlearning involve updating LLM parameters to erase specific knowledge. However, current unlearning paradigms ar…

2023

Multi-Modal Protein Knowledge Graph Construction and Applications (Student Abstract)

AAAI 2023technical

Existing data-centric methods for protein science generally cannot sufficiently capture and leverage biology knowledge, which may be crucial for many protein tasks. To facilitate research in this field, we create ProteinKG65, a knowledge graph for protein science. Using gene ontology and Uniprot kno…

2023

Multimodal Analogical Reasoning over Knowledge Graphs

ICLR 2023poster

Analogical reasoning is fundamental to human cognition and holds an important place in various fields. However, previous studies mainly focus on single-modal analogical reasoning and ignore taking advantage of structure knowledge. Notably, the research in cognitive psychology has demonstrated that i…

2022

CBLUE: A Chinese Biomedical Language Understanding Evaluation Benchmark

ACL 2022long

Artificial Intelligence (AI), along with the recent progress in biomedical language understanding, is gradually offering great promise for medical practice. With the development of biomedical language understanding benchmarks, AI applications are widely used in the medical field. However, most bench…

2022

Contrastive Demonstration Tuning for Pre-trained Language Models

EMNLP 2022finding

Pretrained language models can be effectively stimulated by textual prompts or demonstrations, especially in low-data scenarios. Recent works have focused on automatically searching discrete or continuous prompts or optimized verbalizers, yet studies for the demonstration are still limited. Concrete…

2022

Decoupling Knowledge from Memorization: Retrieval-augmented Prompt Learning

NeurIPS 2022accept

Prompt learning approaches have made waves in natural language processing by inducing better few-shot performance while they still follow a parametric-based learning paradigm; the oblivion and rote memorization problems in learning may encounter unstable generalization issues. Specifically, vanilla…

2022

OntoProtein: Protein Pretraining With Gene Ontology Embedding

ICLR 2022poster

Self-supervised protein language models have proved their effectiveness in learning the proteins representations. With the increasing computational power, current protein language models pre-trained with millions of diverse sequences can advance the parameter scale from million-level to billion-leve…