Zhenlei Xu

PSSM-Distil: Protein Secondary Structure Prediction (PSSP) on Low-Quality PSSM by Knowledge Distillation with Contrastive Learning

Protein secondary structure prediction (PSSP) is an essential task in computational biology. To achieve the accurate PSSP, the general and vital feature engineering is to use multiple sequence alignment (MSA) for Position-Specific Scoring Matrix (PSSM) extraction. However, when only low-quality PSSM…