← Search

Zishen Zhang

2 accepted papers

2025

Latent Retrieval Augmented Generation of Cross-Domain Protein Binders

NeurIPS 2025poster

Designing protein binders targeting specific sites, which requires to generate realistic and functional interaction patterns, is a fundamental challenge in drug discovery. Current structure-based generative models are limited in generating nterfaces with sufficient rationality and interpretability.…

Cited by 0SourceScholar
2025

UniMoMo: Unified Generative Modeling of 3D Molecules for De Novo Binder Design

ICML 2025poster

The design of target-specific molecules such as small molecules, peptides, and antibodies is vital for biological research and drug discovery. Existing generative methods are restricted to single-domain molecules, failing to address versatile therapeutic needs or utilize cross-domain transferability…