A New Concept for Reconstruction of Volumetric Muscle Loss Injuries Using Spatial Robotic Embedded Bioprinting: A Feasibility Study
Omid Rezayof, Mohammad Rafiee Javazm, Yash Kulkarni, Meenakshi Kamaraj, Maryam Tilton, Johnson v. John, Farshid Alambeigi
Abstract
In this study, we introduce a new concept for reconstruction of Volumetric Muscle Loss (VML) injuries and propose the spatial robotic embedded bioprinting technique. As opposed to the traditional layer-by-layer printing, we leverage the support-free nature of embedded bioprinting to print spatial and complex structures of fascicles in a fusiform muscle. To demonstrate feasibility of this concept, we first propose our robotic bioprinting framework including a robotic arm integrated with a custom-designed bioprinting injector. Complementary motion planning algorithms uniquely designed for this printing task are further proposed. Moreover, the effect of embedded bioprinting parameters, as well as the supporting bath and injecting materials compatibility on the uniformity and quality of the printed constructs has been analyzed. Finally, we perform a case study by printing a fusiform muscle-shape construct using the proposed concept and algorithms, and evaluate the quality of the printed structure.
BibTeX
@inproceedings{iros2025_anewconceptforre,
title = {A New Concept for Reconstruction of Volumetric Muscle Loss Injuries Using Spatial Robotic Embedded Bioprinting: A Feasibility Study},
author = {Omid Rezayof and Mohammad Rafiee Javazm and Yash Kulkarni and Meenakshi Kamaraj and Maryam Tilton and Johnson v. John and Farshid Alambeigi},
booktitle = {IROS 2025},
year = {2025}
}