4 accepted papers
Cell penetration is an indispensable step in many cell surgery tasks. Conventionally, cell penetration is achieved by passively indenting and eventually puncturing the cell membrane, during which undesired large cell deformation is induced. Piezo drills have been developed to penetrate cells with le
Automated manipulation of single cells is required in both biological and clinical applications. In clinical infertility treatments, a single motile sperm is immobilized and inserted into an egg cell for in vitro fertilization. Sperm immobilization is essential to ease the ensuing pick-up procedure,
Mammalian sperms reorient against fluid flow in the female reproductive tract, known as rheotaxis. Compared to chemotaxis that provides short-distance guidance, rheotaxis provides long-distance guidance for a sperm to find the egg cell. However, only a low number of sperms are capable of rheotaxis a
This paper reports the first robotic system for vitrification of mammalian embryos. Vitrification is a technique for preserving oocytes and embryos in clinical IVF (in vitro fertilization). The procedure involves multiple steps of stringently timed pick-and-place operation for processing an oocyte/e…