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Dongchen He

3 accepted papers

2026

DS-ProGen: A Dual-Structure Deep Language Model for Functional Protein Design

AAAI 2026technical

Inverse Protein Folding (IPF) is a critical subtask in the field of protein design, aiming to engineer amino acid sequences capable of folding correctly into a specified three-dimensional (3D) conformation. Although substantial progress has been achieved in recent years, existing methods generally r

Cited by 0SourcePDFScholar
2026

RMSAGen: Integrating Multiple Sequence Alignment for Function RNA Design

AAAI 2026technical

Biological sequences, including RNAs and proteins, share similarities with natural languages, enabling the application of advanced language models to various biological tasks. However, due to its flexibility and lack of experimental data, RNA is a particularly challenging biological ``language

Cited by 0SourcePDFScholar
2022

View Dialogue in 2D: A Two-stream Model in Time-speaker Perspective for Dialogue Summarization and beyond

COLING 2022main

Existing works on dialogue summarization often follow the common practice in document summarization and view the dialogue, which comprises utterances of different speakers, as a single utterance stream ordered by time. However, this single-stream approach without specific attention to the speaker-ce…