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Jan-Christian Huetter

6 accepted papers

2025

Contextualizing biological perturbation experiments through language

ICLR 2025poster

High-content perturbation experiments allow scientists to probe biomolecular systems at unprecedented resolution, but experimental and analysis costs pose significant barriers to widespread adoption. Machine learning has the potential to guide efficient exploration of the perturbation space and extr…

2025

Modeling Complex System Dynamics with Flow Matching Across Time and Conditions

ICLR 2025spotlight

Modeling the dynamics of complex real-world systems from temporal snapshot data is crucial for understanding phenomena such as gene regulation, climate change, and financial market fluctuations. Researchers have recently proposed a few methods based either on the Schroedinger Bridge or Flow Matching…

Cited by 1SourcePDFScholar
2024

Learning Identifiable Factorized Causal Representations of Cellular Responses

NeurIPS 2024poster

The study of cells and their responses to genetic or chemical perturbations promises to accelerate the discovery of therapeutics targets. However, designing adequate and insightful models for such data is difficult because the response of a cell to perturbations essentially depends on contextual cov…

2023

NODAGS-Flow: Nonlinear Cyclic Causal Structure Learning

AISTATS 2023poster

Learning causal relationships between variables is a well-studied problem in statistics, with many important applications in science. However, modeling real-world systems remain challenging, as most existing algorithms assume that the underlying causal graph is acyclic. While this is a convenient fr…

2022

Large-Scale Differentiable Causal Discovery of Factor Graphs

NeurIPS 2022accept

A common theme in causal inference is learning causal relationships between observed variables, also known as causal discovery. This is usually a daunting task, given the large number of candidate causal graphs and the combinatorial nature of the search space. Perhaps for this reason, most research…