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Menglu Li

3 accepted papers

2025

Knowledge-Guided Domain Adaptation Model for Transferring Drug Response Prediction from Cell Lines to Patients

AAAI 2025technical

Drug response prediction (DRP) is a longstanding challenge in modern oncology that underpins personalized treatment. Early DRP methods, trained on label-rich cell line samples, suffer from performance degradation when applied to label-scarce patient samples due to the distribution shift. Recently, a…

2024

Improving PTM Site Prediction by Coupling of Multi-Granularity Structure and Multi-Scale Sequence Representation

AAAI 2024technical

Protein post-translational modification (PTM) site prediction is a fundamental task in bioinformatics. Several computational methods have been developed to predict PTM sites. However, existing methods ignore the structure information and merely utilize protein sequences. Furthermore, designing a mor…

2023

Multi-view Contrastive Learning Hypergraph Neural Network for Drug-Microbe-Disease Association Prediction

IJCAI 2023poster

Identifying the potential associations among drugs, microbes and diseases is of great significance in exploring the pathogenesis and improving precision medicine. There are plenty of computational methods for pair-wise association prediction, such as drug-microbe and microbe-disease associations, bu…