Nuowei Liu

2 accepted papers

2026

PDFBench: A Benchmark for De Novo Protein Design from Function

Jiahao Kuang, Nuowei Liu, Changzhi Sun, Jie Wang, Tao Ji, Yuanbin Wu

ICML 2026poster

Function-guided protein design is a crucial task with significant applications in drug discovery and enzyme engineering. However, the field lacks a unified and comprehensive evaluation framework. Current models are assessed using inconsistent and limited subsets of metrics, which prevents fair compa…

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2025

Protein Design with Dynamic Protein Vocabulary

Nuowei Liu, Jiahao Kuang, Yanting Liu, Tao Ji, Changzhi Sun, Man Lan +1

NeurIPS 2025spotlight

Protein design is a fundamental challenge in biotechnology, aiming to design novel sequences with specific functions within the vast space of possible proteins. Recent advances in deep generative models have enabled function-based protein design from textual descriptions, yet struggle with structura…

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