9 accepted papers
Large language models (LLMs) have significantly advanced protein representation learning. However, their capacity to interpret and design antibodies through natural language remains limited. To address this challenge, we present AFD-Instruction, the first large-scale instruction dataset with functio…
Combining Mixture of Experts (MoE) with Low-Rank Adaptation (LoRA) has shown promising efficiency in multi-task instruction tuning for Large Language Models (LLMs). While existing routing schemes for such MoE systems employ auxiliary functions to ensure both expert selection certainty and workload b
Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a cost-effective alternative to expensive ST technologies. Ho
Despite the progress made by multimodal large language models (MLLMs) in computational pathology, they remain limited by a predominant focus on patch-level analysis, missing essential contextual information at the whole-slide level. The lack of large-scale instruction datasets and the gigapixel scal…
Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However existing methods leverage coarse-grained pathogenetic descriptions for visual repre…
Current representation learning methods for whole slide image (WSI) with pyramidal resolutions are inherently homogeneous and flat, which cannot fully exploit the multiscale and heterogeneous diagnostic information of different structures for comprehensive analysis. This paper presents a novel graph…
Fairness has emerged as a critical problem in federated learning (FL). In this work, we identify a cause of unfairness in FL -- conflicting gradients with large differences in the magnitudes. To address this issue, we propose the federated fair averaging (FedFV) algorithm to mitigate potential confl…
This paper investigates the problem of noise-induced annoyance level evaluation, and proposes a novel annoyance measurement metric for more efficient and accurate evaluation of annoyance level of different types of noises. Results from a large-scale subjective listening test using 90 different noise…
A memory-based search circuit is introduced in this paper. In this circuit, the conventional memory structure is customized to provide equality comparison for each column of memory array, and a counting circuit is included at each column to record the degree of matches between query and reference da…