← Search

Ruichen Zhang

4 accepted papers

2026

(Be Cautious!) Bio-Foundation Models Are Not Yet Robust to Biologically Plausible Perturbations and ML Transformations

ICML 2026poster

Though biological foundation models (Bio-FMs) have delivered strong performance across biomedical tasks, their robustness to small-but-real perturbations is underexplored. In this work, we ask: Are Bio-FMs robust for real-world use? What perturbations compromise their reliability? Our pilot study su…

Cited by 0SourceScholar
2026

CAR-LoRA: Training Compression-Aware and Robust LoRA Adapters for Evolving LLMs

ICLR 2026poster

The deployment of large language models (LLMs) for specialized tasks on resource-constrained edge devices like smartphones and sensors presents a significant scalability problem. To run on such hardware, these massive models must be compressed using techniques like \emph{quantization or pruning} to…

Cited by 0SourceScholar
2026

The Quest for Efficient Reasoning: A Data-Centric Benchmark to CoT Distillation

ICLR 2026poster

Data-centric distillation, including data augmentation, selection, and mixing, offers a promising path to creating smaller, more efficient student Large Language Models (LLMs) that retain strong reasoning abilities. However, there still lacks a comprehensive benchmark to systematically assess the ef…

Cited by 0SourcecodeScholar
2025

GRNFormer: A Biologically-Guided Framework for Integrating Gene Regulatory Networks into RNA Foundation Models

ACL 2025finding

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in gene regulatory relationships and fail to leverage multi-omic…

Cited by 0SourcePDFScholar