26 accepted papers
Systematic reviews (SR), in which experts summarize and analyze evidence across individual studies to provide insights on a specialized topic, are a cornerstone for evidence-based clinical decision-making, research, and policy. Given the exponential growth of scientific articles, there is growing in…
Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single molecular species, cryo-EM holds great potential for structure determination of many targets simultaneously in a high-throug
Large Vision-Language Models (VLMs) often answer classic visual illusions "correctly" on original images, yet persist with the same responses when illusion factors are inverted, even though the visual change is obvious to humans. This raises a fundamental question: do VLMs perceive visual changes or
Scaling up multimodal models has enabled remarkable advances in visual understanding and reasoning, but practical demands call for smaller, efficient systems. In this work, we conduct a principled analysis of downscaling intelligence in multimodal models, examining how reduced large language model (
There is growing interest in biomedical vision--language models trained on scientific literature. However, most pipelines compress rich multi-panel figures and long captions into coarse figure-level pairs, discarding the fine-grained correspondences clinicians rely on when zooming into local structu
Existing methods for extracting reward signals in Reinforcement Learning typically rely on labeled data and dedicated training splits, a setup that contrasts with how humans learn directly from their environment.In this work, we propose TTRV to enhance vision-language understanding by adapting the m
The composition of specialized tools offers a powerful approach for complex visual reasoning, particularly for tasks involving 3D spatial understanding. However, existing visual programming methods are often constrained by fixed toolsets or offline tool induction, which leads to suboptimal solutions…
Unified models can handle both multimodal understanding and generation within a single architecture, yet they typically operate in a single pass without iteratively refining their outputs. Many multimodal tasks, especially those involving complex spatial compositions, multiple interacting objects, o
Is basic visual understanding really solved in state-of-the-art VLMs? We present VisualOverload, a slightly different visual question answering (VQA) benchmark comprising 2,720 question-answer pairs, with privately held ground-truth responses. Unlike prior VQA datasets that typically focus on near g
Despite the rapid integration of video perception capabilities into Large Multimodal Models (LMMs), what drives their video perception remains poorly understood. Consequently, many design decisions in this domain are made without proper justification or analysis. The high computational cost of train…
The rapid development of vision language models (VLMs) demands rigorous and reliable evaluation. However, current visual question answering (VQA) benchmarks often depend on open-ended questions, making accurate evaluation difficult due to the variability in natural language responses. To address thi…
The development of vision-language models (VLMs) is driven by large-scale and diverse multi-modal datasets. However, progress toward generalist biomedical VLMs is limited by the lack of annotated, publicly accessible datasets across biology and medicine. Existing efforts are limited to narrow domain…
Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative model that simulates cellular morphology changes induced by chemical and genetic perturbations using flow matching. Unlike…
CLIP outperforms self-supervised models like DINO as vision encoders for vision-language models (VLMs), but it remains unclear whether this advantage stems from CLIP’s language supervision or its much larger training data. To disentangle these factors, we pre-train CLIP and DINO under controlled set
Recent works on accelerating Vision-Language Models achieve strong performance across a variety of vision-language tasks despite highly compressing visual information. In this work, we examine the popular acceleration approach of early pruning of visual tokens inside the language model. Surprisingly…
Large pre-trained models, or foundation models, have shown impressive performance when adapted to a variety of downstream tasks, often out-performing specialized models. Hypernetworks, neural networks that generate some or all of the parameters of another neural network, have become an increasingly…
Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (MLLMs) for AI-assisted research, existing multimodal reasoning benchmarks only target up to college-level difficulty, wh…
Negation is a fundamental linguistic phenomenon that can entirely reverse the meaning of a sentence. As vision language models (VLMs) continue to advance and are deployed in high-stakes applications, assessing their ability to comprehend negation becomes essential. To address this, we introduce NegV…
How do two individuals differ when performing the same action? In this work, we introduce Video Action Differencing (VidDiff), the novel task of identifying subtle differences between videos of the same action, which has numerous applications, such as coaching and skill learning. To enable developme…
The performance and reasoning capabilities of Large Multi-modal Models (LMMs) is dependent on the size and quality of their training datasets. However, collecting datasets that support chain-of-thought instruction tuning is highly challenging. Existing video instruction tuning datasets are often der…
"Neural Radiance Fields (NeRFs) are trained to minimize the rendering loss of predicted viewpoints. However, the photometric loss often does not provide enough information to disambiguate between different possible geometries yielding the same image. Previous work has thus incorporated depth supervi…
How do two sets of images differ? Discerning set-level differences is crucial for understanding model behaviors and analyzing datasets yet manually sifting through thousands of images is impractical. To aid in this discovery process we explore the task of automatically describing the differences bet…
Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis, enhancing researchers’ efficiency, identifying new image biomarkers,…
"Long-form video understanding represents a significant challenge within computer vision, demanding a model capable of reasoning over long multi-modal sequences. Motivated by the human cognitive process for long-form video understanding, we emphasize interactive reasoning and planning over the abili…
"Text-to-image diffusion models generate impressive and realistic images, but do they learn to represent the 3D world from only 2D supervision? We demonstrate that yes, certain 3D scene representations are encoded in the text embedding space of models like Stable Diffusion. Our approach, Viewpoint N…
Image classification is one of the most fundamental capabilities of machine vision intelligence. In this work, we revisit the image classification task using visually-grounded language models (VLMs) such as GPT-4V and LLaVA. We find that existing proprietary and public VLMs, despite often using CLIP…