Xianyong Fang — accepted AI-conference papers

2026

EnzyPGM: Pocket-conditioned Generative Model for Substrate-specific Enzyme Design

Zefeng Lin, Zhihang Zhang, Weirong Zhu, Tongchang Han, Xianyong Fang, Tianfan Fu +1

IJCAI 2026

Designing enzymes with substrate-binding pockets is a critical challenge in protein engineering, as catalytic activity depends on the precise interaction between pockets and substrates. Currently, generative models dominate functional protein design but cannot model pocket-substrate interactions, wh

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2023

Sub-Band Based Attention for Robust Polyp Segmentation

Xianyong Fang, Yuqing Shi, Qingqing Guo, Linbo Wang, Zhengyi Liu

IJCAI 2023poster

This article proposes a novel spectral domain based solution to the challenging polyp segmentation. The main contribution is based on an interesting finding of the significant existence of the middle frequency sub-band during the CNN process. Consequently, a Sub-Band based Attention (SBA) module is…

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