5 accepted papers
Polypharmacology provides a powerful strategy for treating complex diseases, but identifying molecules that simultaneously satisfy coupled constraints across multiple biological targets remains difficult. Existing methods typically model protein pockets in isolation and struggle to jointly account f…
Efficient generation of targeted drug molecules is crucial in the field of drug discovery. Most existing methods neglect the high-order information in the structure of protein pockets, limiting the performance of generated drug molecules. This paper proposes a pocket-aware drug design framework, nam
Dual-view gaze target estimation in classroom environments has not been thoroughly explored. Existing methods lack consideration of depth information, primarily focusing on 2D image information and neglecting the latent 3D spatial context, which could lead to suboptimal transformation and cause the…
Existing works on document image shadow removal mostly depend on learning and leveraging a constant background (the color of the paper) from the image. However, the constant background is less representative and frequently ignores other background colors, such as the printed colors, resulting in dis…
An algorithm that uses low-cost inertial measurement units (IMUs) for estimating link angles for floating base robotic platforms is proposed. Each link has four IMUs attached on its surfaces, and an Extended Kalman Filter (EKF) and a Complementary Filter (CF) are used for fusing the sensors' data. T…