10 accepted papers
Micromanipulation techniques that can achieve controlled fine operations at the micro scale play an important role in biomedical fields including embryo engineering, gene engineering, drug screening, and cell analysis. However, micromanipulation of biological micro-objects, such as cells and micro t…
In recent years, micromanipulation technology has achieved extensive applications in industry and life science. Improving the precision and bandwidth of the micromanipulator and simultaneously reducing size, weight, and cost pose significant challenges to the existing micromanipulator design and fab…
In the last decade, researchers have been trying to develop many microrobots that mimic the extraordinary abilities of bionts in complex environments. How to fabricate the biomimetic microrobot with satisfying deformability and complex shapes to realize desired precise motion is the key issue. In th…
Existing micromanipulation methods, whether contact micromanipulation or non-contact micromanipulation, can hardly meet the requirements of low damage and multiple functions in the biomedical field. This study provides a high-speed micromanipulator that can simulate circular vibrations and generate
The magnetic microrobot has become a promising approach in many biomedical applications due to its small volume, flexible motion, and untethered micromachines. The micro-chain robot is one of the most popular magnetic microrobots. However, the uncontrollable magnetic moment direction and quantity of…
Zebrafish embryo injection is often required in biomedical research using zebrafish. In the injecting operation, trapping and rotating the zebrafish embryo to achieve a proper posture is essential for the high success rate. We proposed an on-chip platform capable of efficient and automatic trapping
Cell stiffness is an essential label-free biomarker used to diagnose and sort cells at the single-cell level. Here, we integrated magnetic tweezers on an efficient cell arraying microfluidic device to evaluate the mechanical properties of single cells. Two motion modes under pulsed electromagnetic f
Three-dimensional multi-layer microfluidic device (MMD) fabricated by polydimethylsiloxane (PDMS) is a solution for on-chip high-complexity serial or parallel processes. In this letter, we propose and set up an automated 8-DOF alignment system assisted by computer vision, which is capable of automat
In this paper, an automated tracking system with head and tail recognition for time-lapse observation of free-moving C. elegans is presented. In microscale field, active C. elegans can move out of the view easily without an automated tracking system because of the narrow field of view and rapid spee…
We have successfully achieved manipulation and assembly of microbeads having the size of 100μm diameter by hemispherical end-effectors with high stability and accuracy. The motivation of achieving assembly of actual cells lies in the great significance of it in tissue regeneration and cell analysis.…