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Yonghong He

6 accepted papers

2026

Learning Protein Structure-Function Relationships through Knowledge-guided Representation Decomposition

ICML 2026poster

Proteins encode diverse functions within complex three-dimensional structures, yet most deep learning representations remain highly entangled, obscuring the biophysical signals that underlie function. Here we introduce ProtDiS, a knowledge-guided framework that decomposes pretrained protein micro-en…

Cited by 0SourceScholar
2026

Turning Pre-Trained Vision Transformers into End-to-End Histopathology Whole Slide Image Models for Survival Prediction

CVPR 2026

Conventional whole slide image (WSI) analysis pipelines follow a two-stage process. First, an image encoder, such as a vision transformer (ViT), is used to perform batched offline feature extraction on a series of tiles cropped from the WSI. Second, a multiple instance learning (MIL) model is traine

Cited by 0SourcecodeScholar
2025

COREMIL: Contextual Position Encoding-based Retrievable Multiple Instance Learning for Slide-level Classification

ICASSP 2025accepted

Multiple Instance Learning (MIL) consists of two stages: feature encoding of instances and feature fusion of instances. This paper identifies two issues in the feature fusion stage of MIL when applied to pathological image classification, which creates performance bottlenecks. First, previous MIL me…

Cited by 0SourceScholar
2024

Dynamic Graph Representation with Knowledge-aware Attention for Histopathology Whole Slide Image Analysis

CVPR 2024poster

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations emphasizing significant instances but struggling to capture the interactions between instance…

2024

HIQ: One-Shot Network Quantization for Histopathological Image Classification

ICASSP 2024accepted

To deploy neural networks on clinical edge devices, quantization is the most commonly used method to compress the models, which requires a calibration set of hundreds of real images. However, due to privacy concerns, the scarcity of private histopathological images hinders the application of quantiz…

Cited by 0SourceScholar
2023

TexQ: Zero-shot Network Quantization with Texture Feature Distribution Calibration

NeurIPS 2023poster

Quantization is an effective way to compress neural networks. By reducing the bit width of the parameters, the processing efficiency of neural network models at edge devices can be notably improved. Most conventional quantization methods utilize real datasets to optimize quantization parameters and…