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Zhongyi Shui

13 accepted papers

2026

Towards Effective and Efficient Context-aware Nucleus Detection in Histopathology Whole Slide Images

AAAI 2026technical

Nucleus detection in histopathology whole slide images (WSIs) is crucial for a broad spectrum of clinical applications. The gigapixel size of WSIs necessitates the use of sliding window methodology for nucleus detection. However, mainstream methods process each sliding window independently, which ov

Cited by 0SourcePDFScholar
2025

Boosting Vision Semantic Density with Anatomy Normality Modeling for Medical Vision-language Pre-training

ICCV 2025poster

Vision-language pre-training (VLP) has great potential for developing multifunctional and general medical diagnostic capabilities. However, aligning medical images with a low signal-to-noise ratio (SNR) to reports with a high SNR presents a semantic density gap, leading to visual alignment bias. In…

2025

CPath-Omni: A Unified Multimodal Foundation Model for Patch and Whole Slide Image Analysis in Computational Pathology

CVPR 2025poster

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration of learned knowledge across patches and WSIs and resulting…

2025

CPathAgent: An Agent-based Foundation Model for Interpretable High-Resolution Pathology Image Analysis Mimicking Pathologists' Diagnostic Logic

NeurIPS 2025poster

Recent advances in computational pathology have led to the emergence of numerous foundation models. These models typically rely on general-purpose encoders with multi-instance learning for whole slide image (WSI) classification or apply multimodal approaches to generate reports directly from images.…

Cited by 0SourceScholar
2025

Large-scale and Fine-grained Vision-language Pre-training for Enhanced CT Image Understanding

ICLR 2025spotlight

Artificial intelligence (AI) shows great potential in assisting radiologists to improve the efficiency and accuracy of medical image interpretation and diagnosis. However, a versatile AI model requires large-scale data and comprehensive annotations, which are often impractical in medical settings. R…

2025

PathGen-1.6M: 1.6 Million Pathology Image-text Pairs Generation through Multi-agent Collaboration

ICLR 2025oral

Vision Language Models (VLMs) like CLIP have attracted substantial attention in pathology, serving as backbones for applications such as zero-shot image classification and Whole Slide Image (WSI) analysis. Additionally, they can function as vision encoders when combined with large language models (L…

2025

PathVQ: Reforming Computational Pathology Foundation Model for Whole Slide Image Analysis via Vector Quantization

NeurIPS 2025poster

Pathology whole slide image (WSI) analysis is vital for disease diagnosis and understanding. While foundation models (FMs) have driven recent advances, their scalability in pathology remains a key challenge. In particular, vision-language (VL) pathology FMs align visual features with language annota…

Cited by 0SourceScholar
2025

Stable Test-Time Training for Semantic Segmentation with Output Contrastive Loss

ICASSP 2025accepted

Deep learning-based models have achieved impressive performance on public segmentation benchmarks, yet generalizing to unseen environments remains challenging. Test-time training (TTT) addresses this by adapting source-pretrained models during evaluation. While existing TTT methods have shown promis…

Cited by 0SourceScholar
2024

DPA-P2PNet: Deformable Proposal-Aware P2PNet for Accurate Point-Based Cell Detection

AAAI 2024technical

Point-based cell detection (PCD), which pursues high-performance cell sensing under low-cost data annotation, has garnered increased attention in computational pathology community. Unlike mainstream PCD methods that rely on intermediate density map representations, the Point-to-Point network (P2PNet…

2024

HLS-FGVC: Hierarchical Label Semantics Enhanced Fine-Grained Visual Classification

ICASSP 2024accepted

Fine-grained visual classification (FGVC) intends to confirm the sub-classes of a specific object category, e.g., identifying the species of dogs or birds. It is a challenging problem with the inter-class similarity among these sub-categories and intra-class variance in every fine-grained class. Mos…

Cited by 0SourceScholar
2024

PathAsst: A Generative Foundation AI Assistant towards Artificial General Intelligence of Pathology

AAAI 2024technical

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural images. However, the field of pathology has largely remained unt…

2024

Rethinking Transformer for Long Contextual Histopathology Whole Slide Image Analysis

NeurIPS 2024poster

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for histopathology WSIs, previous methods typically employ Multi-Instance Learning to enable slide-level prediction gi…

2023

Task-Specific Fine-Tuning via Variational Information Bottleneck for Weakly-Supervised Pathology Whole Slide Image Classification

CVPR 2023poster

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) analysis, such a paradigm still faces performance and generalization problems due to high computational costs and limited supervision of Gigapixel WSIs. To deal with the computation proble…