Zishan Gu

Intervention-Aware Multiscale Representation Learning from Imaging Phenomics and Perturbation Transcriptomics

Microscopy-based phenotypic profiling is scalable for drug discovery but lacks the mechanistic depth of transcriptomics, which remains costly and scarce. Existing multimodal approaches either use images to support other modalities or naively align representations by sample identity, ignoring cell-ty