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Jiayuan Chen

9 accepted papers

2026

Intervention-Aware Multiscale Representation Learning from Imaging Phenomics and Perturbation Transcriptomics

CVPR 2026

Microscopy-based phenotypic profiling is scalable for drug discovery but lacks the mechanistic depth of transcriptomics, which remains costly and scarce. Existing multimodal approaches either use images to support other modalities or naively align representations by sample identity, ignoring cell-ty

Cited by 0SourcecodeScholar
2026

Not Search, But Scan: Benchmarking MLLMs on Scan-Oriented Academic Paper Reasoning

ICLR 2026poster

With the rapid progress of multimodal large language models (MLLMs), AI already performs well at literature retrieval and certain reasoning tasks, serving as a capable assistant to human researchers, yet it remains far from autonomous research. The fundamental reason is that current work on scholarl…

Cited by 0SourcecodeScholar
2026

THEMIS: Towards Holistic Evaluation of MLLMs for Scientific Paper Fraud Forensics

ICLR 2026poster

We present **THEMIS**, a novel multi-task benchmark designed to comprehensively evaluate Multimodal Large Language Models (MLLMs) on visual fraud reasoning within real-world academic scenarios. Compared to existing benchmarks, THEMIS introduces three major advancements. (1) **Real-world Scenarios &…

Cited by 0SourcecodeScholar
2025

DiffAttack: Imperceptible and Transferable Audio Adversarial Attack via Diffusion Model

ICASSP 2025accepted

Recently, adversarial attacks on speaker recognition systems have garnered significant interest. However, existing methods focus on injecting subtle perturbations into audio, which may compromise auditory quality. To address this problem, we propose a novel approach named DiffAttack, which employs a…

Cited by 0SourceScholar
2025

Integrating Biological Knowledge for Robust Microscopy Image Profiling on De Novo Cell Lines

ICCV 2025poster

High-throughput screening techniques, such as microscopy imaging of cellular responses to genetic and chemical perturbations, play a crucial role in drug discovery and biomedical research. However, robust perturbation screening for de novo cell lines remains challenging due to the significant morpho…

2025

The Boundaries of Fair AI in Medical Image Prognosis: A Causal Perspective

NeurIPS 2025poster

As machine learning (ML) algorithms are increasingly used in medical image analysis, concerns have emerged about their potential biases against certain social groups. Although many approaches have been proposed to ensure the fairness of ML models, most existing works focus only on medical image diag…

Cited by 0SourceScholar
2024

Predictive Modeling with Temporal Graphical Representation on Electronic Health Records

IJCAI 2024poster

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal relationships between historical visits and medical events, and the in…

2024

Uncertainty-Aware Yield Prediction with Multimodal Molecular Features

AAAI 2024technical

Predicting chemical reaction yields is pivotal for efficient chemical synthesis, an area that focuses on the creation of novel compounds for diverse uses. Yield prediction demands accurate representations of reactions for forecasting practical transformation rates. Yet, the uncertainty issues broad…

2023

TinyNeRF: Towards 100 x Compression of Voxel Radiance Fields

AAAI 2023technical

Voxel grid representation of 3D scene properties has been widely used to improve the training or rendering speed of the Neural Radiance Fields (NeRF) while at the same time achieving high synthesis quality. However, these methods accelerate the original NeRF at the expense of extra storage demand, w…