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Ziyu Xu

9 accepted papers

2026

Reading the Cell, Designing the Cure: Perturbation-Conditioned Molecular Diffusion for Function-Oriented Drug Design

ICML 2026poster

When reliable target structures are unavailable at scale or phenotypes arise from dysregulated pathways, transcriptomic perturbations provide a system-level functional readout for drug action. In this work, we formalize Transcriptome-based Drug Design (TBDD) as a generative inverse problem: designin…

Cited by 0SourceScholar
2025

L4DR: LiDAR-4DRadar Fusion for Weather-Robust 3D Object Detection

AAAI 2025technical

LiDAR-based 3D object detection is crucial for autonomous driving. However, due to the quality deterioration of LiDAR point clouds, it suffers from performance degradation in adverse weather conditions. Fusing LiDAR with the weatherrobust 4D radar sensor is expected to solve this problem; however, i…

2025

Seg2Box: 3D Object Detection by Point-Wise Semantics Supervision

AAAI 2025technical

LIDAR-based 3D object detection and semantic segmentation are critical tasks in 3D scene understanding. Traditional detection and segmentation methods supervise their models through bounding box labels and semantic mask labels. However, these two independent labels inherently contain significant red…

Cited by 0SourcePDFScholar
2023

Risk-limiting financial audits via weighted sampling without replacement

UAI 2023poster

We introduce the notion of risk-limiting financial audits (RLFA): procedures that manually evaluate a subset of $N$ financial transactions to check the validity of a claimed assertion $\mathcal{A}$ about the transactions. More specifically, RLFA satisfy two properties: (i) if $\mathcal{A}$ is false…

Cited by 5SourcePDFScholar
2020

Class-Weighted Classification: Trade-offs and Robust Approaches

ICML 2020poster

We consider imbalanced classification, the problem in which a label may have low marginal probability relative to other labels, by weighting losses according to the correct class. First, we examine the convergence rates of the expected excess weighted risk of plug-in classifiers where the weighting…